Globally, 242 million people suffer from osteoarthritis. Many are elderly due to simple aging factor, but the occurrence in younger generations has increased due to factors as obesity, jobs that result in high levels of joint stress and contact sports like Ice hockey and football. Untreated or undiagnosed early cartilage damages in younger patients will for sure results in OA progression.
The consequences of OA progression are acute and chronic pain, disability in different levels, fatigue and premature ageing with loss of functioning in society. In addition, OA is associated to increased co-morbidities and other chronic diseases. Common co-morbidities in OA include cardiovascular diseases, diabetes, obesity, lung disease, chronic pain and depression.